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KMID : 0370220120560050320
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Yakhak Hoeji
2012 Volume.56 No. 5 p.320 ~ p.325
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Antibacterial and Antioxidant Activities of the Essential Oil from the Roots of Anthriscus sylvestris
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Lim Hye-Rim
Shin Seung-Won
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Abstract
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To develop a new effective and safe natural antibiotics and antioxidant the essential oil was extracted from the roots of Anthriscus sylvestris by steam distillation. Its composition was analyzed by GC-MS. The activities of the essential oil fraction and its main components were evaluated against antibiotic-susceptible and -resistant strains of some food-born bacteria. In addition the synergism was examined with this oil combined with antibiotic by checkerboard titer test. The antioxidant activities were determined by in 1,1-diphenyl-2-picryl-hydrazil (DPPH) free radical scavenging activity test and reducing power assay. The essential oil fraction of A. sylvestris revealed significant inhibiting activities against antibiotic-susceptible and -resistant species of Vibrio and Shigella with MICs ranged from 1.00~4.00 mg/ml. It showed synergistic or additive effects when it was combined with amphicillin or trimethoprim/sulfamethoxazole (1 : 9). Additionally, the essential oil fraction of A. sylvestris exhibited significant DPPH free radical scavenging activity and the reducing power.
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KEYWORD
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essential oil, Anthriscus sylvestris, myristicin, antibacterial, Shigella, Vibrio, anti-oxidant
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